[Diabetic angiopathy--etiopathogenesis and clinical manifestations (hypersyndrome X)].

Diabetic angiopathy is a generalised systemic disease of the vascular system which afflicts both distribution vessels (diabetic macroangiopathy) and microcirculation (diabetic microangiopathy). The diabetic angiopathy, as well as other angiostenotic diseases (obliterations, obstructions, occlusions) result in one common consequence--ischaemia. This study is based on an analysis of a large group of patients (71,662 angiologic consultant examinations which took place during the 25-year period of the existence of the Comenius University Faculty Hospital). The author indicates that the clinical course of angio-organic ischaemic syndromes determined by diabetic angiopathy is multiform, remarkably severe and unfavourable. The author has suggested the term "X hypersyndrome" referring to cases with simultaneous occurrence of various pathophysiologic abnormalities and clinical units which finally increase the risk of origin and development of diabetic angiopathy. (Tab. 7, Ref. 47.)